In the biopharmaceutical, fine chemical, and life sciences industries, chromatography and purification are essential processes for separating target compounds, removing impurities, and achieving the required product purity.

Whether used for protein purification, bioactive compound extraction, or chemical separation, reliable fluid transfer plays an important role in maintaining efficient and consistent operations.

As processing volumes increase, chromatography and purification systems require pumping solutions that combine high flow capacity, stable operation, flexible control, and easy maintenance.

The Kamoer M7 Industrial Peristaltic Pump is designed to meet these requirements. Featuring a DC servo motor, a robust 733A pump head, and a maximum reference flow rate of up to 33 L/min, the M7 provides a practical solution for large-volume fluid transfer and auxiliary liquid handling in chromatography and purification processes.

 

 

1. Fluid Transfer Challenges in Chromatography and Purification

Chromatography separates compounds based on differences in their interactions with the stationary and mobile phases. Throughout the purification process, reliable liquid handling is required for buffer preparation, fluid transfer, system flushing, and other supporting operations.

High Flow Capacity for Large-Scale Processing

Industrial chromatography and purification systems often involve substantial volumes of buffers, process liquids, and cleaning solutions.

As production capacity expands, pumping equipment must provide sufficient flow capacity to support efficient liquid transfer and minimize processing delays.

Stable Fluid Delivery for Process Consistency

Purification workflows typically involve multiple sequential operations, making reliable fluid handling essential.

Unstable flow, tubing wear, or unexpected pump downtime may disrupt the process and reduce operational efficiency. A dependable pumping system with adjustable flow capability helps support consistent operation.

Automation and Process Integration

Modern biopharmaceutical and chemical processing equipment increasingly relies on automated control systems.

Pumps must not only deliver fluids but also integrate with equipment controllers to support remote operation, adjustable parameters, and automated processing sequences.

Simplified Maintenance and Reduced Contamination Risk

Fluid-contact design is particularly important in applications involving frequent media changes or cleaning procedures.

Peristaltic pumps transfer fluids by compressing flexible tubing. During normal operation, the pumped liquid contacts the inner surface of the tubing rather than the pump's mechanical drive components.

This design helps simplify fluid-path maintenance and reduces the risk of contamination associated with direct contact between process fluids and mechanical pumping components.

 

 

2. Kamoer M7: Designed for High-Flow Industrial Fluid Transfer

The Kamoer M7 Industrial Peristaltic Pump combines high flow capacity, servo motor control, and flexible operating modes to support demanding industrial fluid transfer applications.

[Image 2: Kamoer M7 Industrial Peristaltic Pump product photograph]

01. High Flow Capacity up to 33 L/min

Equipped with a 733A pump head, the M7 supports multiple tubing sizes to accommodate different flow requirements.

When fitted with 92# tubing, the pump delivers a maximum reference flow rate of up to 33 L/min under specified test conditions.

This makes it suitable for applications such as buffer transfer, large-volume liquid handling, and other high-flow processing operations.

Different tubing configurations allow users to select the flow capacity appropriate for their systems.

Note: The maximum flow rate of 33 L/min is measured using water under standard atmospheric conditions without outlet pressure. Actual flow rates may vary depending on fluid properties, tubing configuration, operating speed, and system backpressure.

02. DC Servo Motor for Flexible Flow Adjustment

The M7 is powered by a DC servo motor, offering a speed range of 0.1–360 rpm with a speed adjustment resolution of 0.1 rpm.

This allows operators to adjust the pumping speed according to specific process requirements.

Whether transferring liquids between vessels, supplying process equipment, or performing volume-based dispensing, the M7 provides flexible speed control for different operating conditions.

03. Industrial Pump Head for Reliable Operation

The M7 features a robust 733A industrial pump head with a four-roller configuration.

Its 4.8 mm wall-thickness tubing is designed to accommodate demanding fluid transfer applications, subject to the tubing material and operating conditions.

The pump head incorporates durable metal and engineering-material components to support industrial use.

The tubing-based pumping mechanism also enables convenient inspection and replacement of the fluid-contact component.

With appropriate tubing selection, operating parameters, and preventive maintenance, the M7 can help reduce the risk of unplanned downtime.

04. Multiple Operating Modes for Different Process Requirements

The M7 features a 3.5-inch display and physical control buttons for convenient operation.

It supports several operating modes:

• Manual Mode: For routine liquid transfer and equipment setup.

• Dispensing Mode: For fluid delivery based on preset dispensing volumes.

• Calibration Mode: For calibrating tubing flow performance under actual operating conditions.

• Modbus-RTU Mode: For remote control through a compatible communication interface.

These operating modes provide flexibility for both standalone operation and automated equipment integration.

05. External Control for Automated Equipment Integration

For chromatography and purification equipment manufacturers, seamless integration with existing control systems is an important consideration.

The M7 supports RS485 communication and digital input control, allowing the pump to be integrated into automated processing equipment.

Additional analog and I/O control functions are available through customization, providing further flexibility for OEM system development.

 

 

3. Typical Applications in Chromatography and Purification

The Kamoer M7 is particularly suitable for auxiliary fluid-handling operations requiring high flow capacity and adjustable pumping speed.

Application 1: Buffer Preparation and Transfer

Buffers are widely used in chromatography processes, including protein purification and other biopharmaceutical separation applications.

Buffer preparation, storage, and transfer often involve substantial liquid volumes.

The M7 can be used to transfer buffer solutions between storage vessels or deliver prepared buffers to suitable processing equipment.

Its high flow capacity and adjustable speed help accommodate different transfer volumes and operating requirements.

Application 2: Auxiliary Fluid Supply for Purification Systems

Some low-pressure purification systems and supporting process operations require adjustable liquid delivery.

The M7 provides flexible speed control and external communication capabilities, making it an option for auxiliary fluid supply where flow, pressure, and chemical compatibility requirements are met.

For direct chromatography column feeding, sample loading, or elution applications, system backpressure, flow stability, and process accuracy requirements must be evaluated before selecting a pump.

Application 3: System Flushing and Liquid Replacement

Chromatography and purification equipment often requires flushing, liquid replacement, and routine maintenance.

The M7 can support the transfer of compatible flushing liquids and assist with automated fluid-handling operations.

Its tubing-based fluid path also makes it easier to inspect and replace fluid-contact components according to process requirements.

 

4. Kamoer M7 Technical Specifications

Parameter	Specification
Model	M7
Pump Head	733A
Motor Type	DC Servo Motor
Maximum Reference Flow Rate	33 L/min
Speed Range	0.1–360 rpm
Speed Resolution	0.1 rpm
Tubing Wall Thickness	4.8 mm
Number of Rollers	4
Motor Service Life	≥6,000 hours
Display	3.5-inch Display
Operating Modes	Manual, Dispensing, Calibration, Modbus-RTU
External Control	Digital Input, RS485; additional options available through customization
Power Supply	AC 100–240 V

Maximum Reference Flow Rate by Tubing Size

Tubing Size	Inner Diameter	Maximum Flow Rate
88#	12.7 mm	12 L/min
92#	25.4 mm	33 L/min
189#	15.9 mm	18 L/min
191#	19.0 mm	20 L/min

All flow rates are reference values measured under specified test conditions. Actual performance depends on fluid properties, system backpressure, tubing characteristics, and operating conditions.

 

5. How to Select a Pump for Chromatography and Purification

Different chromatography and purification systems have different requirements for flow capacity, pressure, fluid compatibility, and automation.

When selecting a pumping solution, equipment manufacturers and system integrators should consider the following factors:

Flow Requirements

Determine the required flow range and whether adjustable flow rates are needed for different process stages.

System Backpressure

Evaluate tubing resistance, outlet pressure, and pressure variations throughout the fluid transfer process.

Chemical Compatibility

Select suitable tubing based on the chemical composition of buffers, cleaning solutions, and other process liquids.

Operating Conditions

Consider continuous operation requirements, start-stop frequency, maintenance intervals, and expected tubing life.

Automation and Control

Confirm whether the pump needs to communicate with a PLC, process controller, or other automated equipment.

It is important to note that chromatography applications may have significantly different requirements for flow accuracy, pulsation, and pressure.

For high-backpressure or high-precision chromatography applications, pump suitability should be evaluated based on actual operating conditions rather than maximum flow capacity alone.

 

6. Reliable Fluid Transfer Solutions from Kamoer

From laboratory-scale liquid handling to industrial processing, reliable fluid transfer is essential for efficient chromatography and purification operations.

The Kamoer M7 Industrial Peristaltic Pump combines high flow capacity, DC servo motor control, multiple operating modes, and external communication capabilities to support a wide range of fluid transfer requirements.

As a fluid handling equipment manufacturer, Kamoer provides peristaltic pumps, diaphragm pumps, and customized pumping solutions for medical equipment, laboratory instruments, biopharmaceutical processing, and industrial automation applications.

 

Looking for a Reliable Pumping Solution for Your Chromatography or Purification System?

Contact the Kamoer technical team with your required flow rate, fluid properties, system backpressure, and operating conditions.

Our team can help evaluate suitable pump configurations and identify the right fluid transfer solution for your application.

Contact Kamoer for Pump Selection and Technical Support.